Journal of Liver Cancer

Young Jun Kim

2 Articles

Treatment of Small Hepatocellular Carcinoma by Transarterial Chemoembolization and Consecutive Radiofrequency Ablation: Byung Kook Kim, So Young Kwon, Soon-Young Ko, Won Hyeok Choe, Chang Hong Lee, Min Woo Lee, Young Jun Kim, Sang Woo Park; Journal of the Korean Liver Cancer Study Group. 2008;8(1):115-119. Published online June 30, 2008

Abstract PDF: Surgical resection has been considered to be the best treatment for early-stage hepatocellular carcinoma (HCC). However, radiofrequency ablation (RFA) has been reported to be more effective than other local ablation treatments and transarterial chemoembolization (TACE) in achieving complete tumor necrosis. Recently, combined chemoembolization and RFA may improve both overall and recurrence-free survival rates in patients with early stage HCC. RFA have not been applied in cases of that tumors were non-visualization on ultrasonography, and located near by large vessels, main bile ducts, and major extra-hepatic organs. we found that tumor, which was not shown on ultrasonography before TACE, can be visible for several days just after TACE. We report the clinical course and complete necrosis of tumor in two cases of small HCC by TACE and consecutive RFA within a few days.

Spontaneous Total Necrotic Hepatocellular Carcinoma: Young Jun Kim, Jun Yong Jeong, Kyong Ho Lee, Se Hyung Kim, Joon Koo Han, Byung Ihn Choi; Journal of the Korean Liver Cancer Study Group. 2002;2(1):73-75. Published online July 31, 2002

Abstract PDF: Spontaneous total necrosis of hepatocellular carcinoma is extremely rare, with only 16 cases reported in the English literature. In this report, we describe a case of spontaneous totally necrotic hepatocellular carcinoma in a 53-year-old man who was previously healthy. The hepatic mass was incidentally found. The viral markers for hepatitis B and C were negative and alpha-fetoprotein was normal. Ultrasonography revealed hypoechoic mass with peripheral high echoic rim. On CT, the mass was hypodense in both hepatic arterial phase and portal venous phase. Subtle capsular enhancement was noted in portal venous phase CT. The patient underwent hepatic segmentectomy. The resected hepatic segment revealed 4.5 cm sized, well encapsulated, and nearly totally necrotic mass. On microscopic examination, the ghost cells of hepatocellular carcinoma were found in totally necrotic tissue, supporting diagnosis of hepatocellular carcinoma.